Category: Genomics

  • Adam and Eve: a tested hypothesis?

    Does genomic evidence make it scientifically impossible that the human lineage could have ever passed through a population bottleneck of just two individuals? This is a question I am asked semi-frequently by religious friends. With my current understanding of the genetic evidence, I can’t state categorically that it’s impossible. In this view, I find I differ […]

  • “Abundant bioactivity” of random DNA sequences?

    This blog was written for the Nature Ecology and Evolution Community where it is posted here. Probing the claims of a recent study Readers of this blog will be aware of the recent Nature Ecology and Evolution paper entitled “Random sequences are an abundant source of bioactive RNAs or peptides”. Rafik Neme, the first author, […]

  • The evolutionary mystery of orphan genes

    Every newly sequenced genome contains genes with no traceable evolutionary descent – the ash genome was no exception This week in Nature I and my co-authors published the ash tree genome. Within it we found 38,852 protein-coding genes. Of these one quarter (9,604) were unique to ash. On the basis of our research so far, […]

  • Ash tree genomics in response to ash dieback

    The ash tree genome project published in Nature today began, for me, with a lunchtime conversation with Andrew Leitch in the SCR bar at Queen Mary University of London in early November 2012. Ash dieback had been found in natural woodland in England for in late October. Such was the seriousness of the likely environmental […]

  • Telegraph article: British woodlands need diversity from around the world

    This article was written for The Daily Telegraph and is published online here. Foreign tree species are needed to help preserve Britain’s woodlands from disease, argues Dr Richard Buggs. Trees in Britain do not have enough genetic diversity to cope with a global influx of pathogens. As global trade introduces new pests and diseases, we […]