Adam and Eve: lessons learned

This blog was first posted at Nature Ecology & Evolution Community on 14 April 2018 Preliminary conclusions about the possibility of a short, sharp human bottleneck A few months ago I asked this community if modern genome science had tested an “Adam and Eve” hypothesis that the human lineage has passed through short, sharp bottleneck […]

Adam and Eve: a tested hypothesis?

This blog was written for the Nature Ecology and Evolution Community where it is posted here. Comments on a recent book chapter Does genomic evidence make it scientifically impossible that the human lineage could have ever passed through a population bottleneck of just two individuals? This is a question I am asked semi-frequently by religious […]

“Abundant bioactivity” of random DNA sequences?

This blog was written for the Nature Ecology and Evolution Community where it is posted here. Probing the claims of a recent study Readers of this blog will be aware of the recent Nature Ecology and Evolution paper entitled “Random sequences are an abundant source of bioactive RNAs or peptides”. Rafik Neme, the first author, […]

The evolutionary mystery of orphan genes

This blog was written for the Nature Ecology and Evolution Community where it is posted here. Every newly sequenced genome contains genes with no traceable evolutionary descent – the ash genome was no exception This week in Nature I and my co-authors published the ash tree genome. Within it we found 38,852 protein-coding genes. Of […]

Ash tree genomics in response to ash dieback

This blog was written for the Nature Ecology and Evolution Community where it is posted here. The ash tree genome project published in Nature today began, for me, with a lunchtime conversation with Andrew Leitch in the SCR bar at Queen Mary University of London in early November 2012. Ash dieback had been found in […]